5-O-Acetyl-d-ribono-1,4-lactone
نویسندگان
چکیده
The title compound, C(7)H(10)O(6), was obtained from a regioselective enzyme-catalysed acyl-ation of d-ribono-1,4-lactone. The five-membered ring of the acyl-ated sugar shows an envelope conformation. In the crystal, the mol-ecules are linked by inter-molecular O-H⋯O hydrogen-bonds, forming a one-dimensional polymeric structure parallel to [010]. In addition, packing analysis shows stacking along the b axis.
منابع مشابه
Crystal structure of 5-O-benzoyl-2,3-O-isopropylidene-d-ribono-1,4-lactone
In the title compound, C15H16O6, obtained from the acyl-ation reaction between 2,3-O-iso-propyl-idene-d-ribono-1,4-lactone and benzoyl chloride, the known absolute configuration for the lactone moiety of the ester substituent has been confirmed. The five-membered rings of the bicyclic lactone-dioxolane moiety both show envelope conformations and form a dihedral angle of 19.82 (7)° between the l...
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The crystal structure of the title compound, C(13)H(14)O(5), establishes (i) the (S) - rather than (R) - configuration at the acetal carbon and (ii) that both the acetal and the lactone form five- rather than six-membered rings; the absolute configuration is determined by the use of 2-C-methyl-d-ribono-1,4-lactone as the starting material. The compound consists of hydrogen-bonded chains of mol-...
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R ene C suk *a, Petra Dörrb, Martin Kühnb, Claus Krieger0, and M ikhael Y. A ntipind a Institut für Organ. Chemie, Martin-Luther-Universität Halle-Wittenberg, Kurt-Mothes-Str. 2, D-06120 Halle (Saale), Germany h Pharmazeutisch-Chemisches Institut. Universität Heidelberg, Im Neuenheimer Feld 364, D-69120 Heidelberg. Germany c Max-Planck-Institut für Medizinische Forschung, Jahn-Straße 29, D-6912...
متن کاملSynthesis of polyhydroxy amino acids based on D- and L-alanine from D-glycero-D-gulo-heptono-1,4-lactone.
2-Amino-2,3-dideoxy-D-manno-heptonic acid (7) has been synthesized from 2,5,6,7-tetra-O-acetyl-3-deoxy-D-gluco-heptono-1,4-lactone (1), which was readily prepared from D-glycero-D-gulo-heptono-1,4-lactone. O-Deacetylation of 1 followed by treatment with 13:1 (v/v) 2,2-dimethoxypropane/acetone in the presence of p-toluenesulfonic acid gave methyl 3-deoxy-4,5:6,7-di-O-isopropylidene-D-gluco-hepto...
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عنوان ژورنال:
دوره 67 شماره
صفحات -
تاریخ انتشار 2011